Immunohistochemistry Kits and Reagents
Biotium Cytokeratin 8/18(B22.1 + B23.1), Biotin conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S an
Biocare Medical, LLC DAB SUBSTRATE BUFFER 25ML
DAB is a permanent chromogen that produces a brown stain in the presence of horseradish peroxidase. This two-component system consists of a liquid stable DAB chromogen and DAB substrate buffer, DAB Chromogen sold seperately.
Biotium Cytokeratin 8(C-43), CF740 conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Biocare Medical, LLC Tween 20 - 100 ml
Tween 20 is a detergent (surfactant) commonly added to buffers and reagents for immunohistochemistry. Its purpose is to decrease background staining and enhance reagent spreading in automated and manual procedures. It can also be used on an automated staining system.
ABclonal Technology RAP1A + RAP1B Rabbit mAb
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]
ABclonal Technology Phospho-MAP2K6-S207/MAP2K3-S189 Rabbit pAb
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Genscript Corporation Nectin-4 HisCynomolgus
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions the latter including specifically interactions with NECTIN1 Does not act as receptor for alpha-herpesvirus entry into cells (Microbial infection) Acts as a receptor for measles virus
Meridian Life Science Lyo-Ready Direct RNA/DNA, 5ML
Lyo-Ready RNA/DNA qPCR Urine is a glycerol-free, high-concentration, ready-to-use RT-qPCR formulation engineered with a proprietary buffer system designed for overcoming inhibitors found in urine. It allows accurate target amplification direct from urine or pooled urine samples. It can be used in multiplex assays that require minimal sample processing and fast turn-around times without compromising sensitivity, for low copy number samples. It also increase reproducibility in extracted samples, as extraction methods are not always 100% efficient, often resulting in loss of target nucleic acid and potential co-purification of urine PCR inhibitors that can interfere with amplification, leading to false-negative results. It is ideal for room temperature, lyophilized, singleplex and multiplex RT-qPCR assays and is suited for high-throughput, automated platforms or microfluidic qPCR platforms.
Meridian Life Science Lyo-Ready Direct RNA/DNA, 50ML
Lyo-Ready RNA/DNA LAMP Stool mix combines even greater tolerance with fast, robust isothermal amplification to enable highly sensitive direct detection using crudely processed stool samples. The mix is uniquely designed to overcome much higher concentrations of inhibitors, and so do not require a DNA or RNA purification step to concentrate and purify a patient sample. Very fast reaction kinetics result in faster time to results and superior amplification sensitivity and specificity. In addition, the 4x concentrated master mix is formulated with lyo-excipients which are optimized for freeze-drying to create ambient-temperature stable assays, making it ideal for POC stool testing.
Meridian Life Science Lyo-Ready Direct RNA/DNA, 50ML
Lyo-Ready RNA/DNA LAMP Urine mix combines even greater tolerance with fast, robust isothermal amplification to enable highly sensitive direct detection using crudely processed urine samples. The mix is uniquely designed to overcome much higher concentrations of inhibitors, and so do not require a DNA or RNA purification step to concentrate and purify a patient sample. Very fast reaction kinetics result in faster time to results and superior amplification sensitivity and specificity. In addition, the 4x concentrated master mix is formulated with lyo-excipients which are optimized for freeze-drying to create ambient-temperature stable assays, making it ideal for POC urine testing.
Meridian Life Science Lyo-Ready LAMP Mix 4x, 500ML
Lyo-Ready LAMP Mix 4x is a glycerol-free mix for use in loop-mediated isothermal amplification (LAMP). It combines the latest advances in buffer chemistry and reaction enhancers, together with an optimized concentration of strand-displacing Polymerase, dNTP and proprietary lyo-excipients allowing ambient temperature stabilization through lyophilization. Lyo-Ready LAMP Mix has been designed for fast, sensitive and highly reproducible DNA target amplification. In order to produce lyophilized ambient-temperature stable LAMP assays, specific primers need to be added prior to lyophilization.
Bioss 1-Catenin - Tyr-228 Phosphos
1-Catenin (Tyr-228) Primary Antibody Unconjugated Host Species Mouse Target Species Human Mouse Rat Clonality Monoclonal Applications WB M356Concentration Size 100 ul Storage Buffer PBS 1 mg/ml BSA 0 05% NaN3 and 50% glycerol